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The team of clinicians and scientists from Dexeus Fertility, the Department of Reproductive Medicine of Dexeus University Hospital in Barcelona (Spain), attended the annual Congress of the European Society of Human Reproduction and Embryology (ESHRE), which was held in Amsterdam from 7 to 10 July.
They presented 9 lectures and 5 posters, sharing the results of their research with the world. This included studies on the most important issues in reproductive health, such as the impact of environmental pollution on fertility, the use of Artificial Intelligence to select the best embryo, and the development of new strategies to improve embryo implantation. The team presented work led by our local Dexeus Fertility team, as well as the results of national and international collaborations.
The papers led by researchers Valeria Donno and Sebastian Leathersich, Fertility Specialist at City Fertility in Perth (Australia) and PhD candidate at Dexeus Fertility, were among those nominated for the Clinical Science Award and the Fertility Society of Australia and New Zealand Exchange Award.
Keep reading to see all of the studies presented by our team in Amsterdam this year.
Abstract citation ID: deae108.027
O-027 Efficacy results from the phase II randomized clinical trial: OXO-001 in infertile women undergoing egg donation IVF/ICSI
A. Arbat, J. Bellver, J. Garcia-Velasco, H. Visnova, R. Kurzawa, A. Gosalvez, N. P. Polyzos, J. J. Espinós, R. Trinchant, M. Llorens, R. Torres, I. Canals
This proof-of-concept (PoC) prospective randomized and controlled study shows that OXO-001 treatment increases implantation and pregnancy rates in infertile women undergoing IVF/ICSI with studied doses.
Abstract citation ID: deae108.080
O-074 Dual trigger is not superior to GnRH Agonist alone for final oocyte maturation in elective fertility preservation. A Randomized Controlled Trial
V. Donno, A. R. Neves, S. Garcia Martinez, N. P. Polyzos
Adding hCG to GnRH-a for triggering final oocyte maturation does not increase the number of MII oocytes in elective fertility preservation cycles.
Abstract citation ID: deae108.081
O-075 Particulate matter (PM2.5 and PM10) exposure prior to oocyte collection is associated with decreased live birth rates in subsequent frozen embryo transfers
S. Leathersich, C. Roche, M. Walls, E. Nathan, R. Hart
Increasing PM10 and PM2.5 exposure prior to OPU is associated with decreased odds of live birth in subsequent FET, independent of the conditions at FET.
Abstract citation ID: deae108.166
O-147 Role of serum progesterone levels and subcutaneous progesterone supplementation in endometriosis patients undergoing artificial cycle frozen embryo transfer
N. Sachs Guedj, B. Coroleu, M. Álvarez, S. García, N. P. Polyzos
Endometriosis patients have comparable progesterone levels before transfer to those without endometriosis. Progesterone supplementation results in similar live birth rate (LBR) to the general population.
Abstract citation ID: deae108.182
O-163 The effect of ambient exposure to air pollutants on live birth rates in frozen embryo transfer cycles
M. Solsona Caba, S. Leathersich, V. Donno, I. Rodriguez, N. Polyzos
Environmental exposure to increased concentrations of CO either on oocyte retrieval or embryo transfer day negatively influences clinical outcomes in FET cycles.
Abstract citation ID: deae108.283
O-240 Embryo assessment: the Istanbul consensus revised
G. Coticchio, A. Ahlström, G. Arroyo, B. Balaban, A. Campbell, M. J. De Los Santos Molina, T. Ebner, D. Gardner, B. Kovacic, K. Lundin, C. Magli, S. Mcheik, D. Morbeck, L. Rienzi, I. Sfontouris16, N. Vermeulen, M. Alikani
The present ESHRE/Alpha Scientists in Reproductive Medicine consensus document provides several novel recommendations to assess oocyte and embryo morphology and rank embryos for transfer.
Abstract citation ID: deae108.284
O-241 ESHRE guidance on embryo transfer: when to do DET?
Z. Veleva, A. Alteri, G. Arroyo, G. Baccino, L. Craciunas, C. De Geyter, S. Santos-Ribeiro, T. Ebner, K. Kordic, H. Mertes, D. Pavicic Baldani, K. Rodriguez-Wallberg, I. Rugescu, K. Tilleman, B. Woodward
The aim of the presentation is to highlight the place of double embryo transfer in the current practice of ART while taking into account best evidence from clinical studies.
Abstract citation ID: deae108.296
O-249 METAPHOR: METabolic imaging through AI-powered Phasor-based Hyperspectral analysis and Organelle recognition for the classification of human blastocysts
S. Ojosnegros, A. Parra, O. Massafret, X. Burgos-Artizzu, A. Ferrer-Vaquer, M. Ares, D. Denkova, M. Parriego, M. Solé, M. Boada, A. Seriola
HS imaging can significantly enhance our classification of human embryos and reveal numerous cellular features present in the embryo invisible to brightfield imaging.
Abstract citation ID: deae108.343
O-290 Reduced uterine artery pulsatility index (UtAPI) in artificial frozen embryo transfer pregnancies leads to underestimation of 1st-trimester preeclampsia risk. An analysis of over 30,000 pregnancies
N. P. Polyzos, V. Donno, I. Rodríguez Garcia
A significant reduction in UtAPI during 1st-trimester screening is observed in artificial frozen embryo transfer (AC-FET) pregnancies, resulting in underestimated preeclampsia risk.
Abstract citation ID: deae108.476
P-102 Incorporation of an automated sperm counting method: a matter of time
M. Ballester, M. Parriego, L. Coll, S. Garcia, T. Freour, N. P. Polyzos, M. Boada
A fully-automated sperm counting system is a reliable tool that significantly reduces time spent for semen evaluation.
Abstract citation ID: deae108.801
P-452 A decrease in serum progesterone-levels (P4) during early luteal phase in modified-natural frozen embryo transfer (mNC-FET) is significantly associated with lower pregnancy rates
M. Alvarez, N. P. Polyzos, I. Rodríguez, N. Sachs-Guedj, M. Solé, B. Coroleu
A P4 decrease (-DP4) through luteal phase in mNC-FET is significantly associated with lower OPR and higher MR compared to P4 increase (þDP4).
Abstract citation ID: deae108.893
P-556 Genetic variation in genes related to folliculogenesis and steroidogenesis in Caucasian and Asian women: Baby steps towards a pharmacogenetic approach in assisted reproductive techniques
A. R. Neves, L. Casarini, S. Garcia, N. L. Vuong, C. Blockeel, M. Simoni, N. P. Polyzos
SMAD2 rs13381619 and COMT rs4680 variants are associated with the follicular output rate (FORT).
Abstract citation ID: deae108.910
P-576 Pharmacokinetic and pharmacodynamic modelling to explore dosing regimens of corifollitropin alfa for ovarian stimulation without the need for additional daily recFSH injections
H. M. Fatemi, N. Polyzos, P. Larsson, B. Mannaerts
For 94% of IVF patients, ovarian stimulation can be safely completed with a maximum of two CFA injections.
Abstract citation ID: deae108.937
P-605 Effectiveness of follitropin delta in patients with potentialpoor response: A post hoc analysis from the ESTHER-1 trial
R. Lobo, I. E. Jepsen, A. Falahati, N. P. Polyzos, J. A. García-Velasco, A. Pinborg, E. Gravotta
Individualised follitropin delta dosing provides a favourable efficacy and safety balance and is as good as follitropin alfa in patients with potential poor ovarian response.
Human Reproduction
Volume 39, Issue Supplement_1 July 2024
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